AFA™ provides precise process control which is beneficial to a number of scientific disciplines in both advanced biological and chemical applications. Covaris AFA and its high level of experimental condition control enables a process to be developed and/or improved upon very quickly, easily and reproducibly.

Covaris provides versatile tools for a broad range of applications, including:

Genomics

• Controlled DNA shearing for next generation sequencing and library construction
• RNA extraction from various biological fluids and tissues, especially difficult tissues, such as skin, bones, corneal, muscle, seeds, leaves, etc.
• Chromatin Shearing for ChIP Analysis for evaluating in vivo interaction of proteins with specific genomic DNA regions.

• Cell/tissue disruption for protein targets and biomarker extraction
• Protein digestion in various substrates

• Tissue Disruption
• Tissue Homogenization
• Cell Lysis
• Plasma Preparation/Extraction

• Compound dissolution and resolution
• Compound formulation
• ADME/Tox
• Tablet Disruption for Pharmaceutical Quality Control
• Liposome preparation
• Emulsions
• Nanoparticle dissolution and micronization

The Covaris AFA is a basic technology which gives superior results in fluidization and mixing. In addition to providing instruments and consumables, we also offer custom research on various Specialized Sample Preparations, such as:

• sample preparation for in vitro diagnostic applications
• emulsion and flow cell related applications