APPLICATIONS Overview   RNA Extraction   Drug Metabolism   Compound Dissolution   Compound Formulation   Liquid Membrane Vesicle Preparation   DNA shearing   Plasma Extraction   Cryo-Pulverization   Specialized Applications   Publications			Publications Use of the Covaris AFA process is constantly expanding. Independent publications and presentations from our customer base can be found below. Application Area Homogenization / Extraction Millennium Pharmaceuticals Poster presented at ASMS 2004 for use of Covaris AFA in tissue extraction Millennium ASMS Poster (90kb)   Rosetta Inpharmatics LLC/Merck & Co Poster presented at CHI Sample Prep 2004 for use of Covaris AFA in tissue extraction CHI Sample Prep 2004 Poster (1.07mb)   Johnson & Johnson Pharmaceutical R&D Poster presented at 2006 ASMS Conference on Mass Spectrometry for use of Covaris AFA for tissue homogenization prior to bioanalysis ASMS 2006 Poster (97kb)   GlaxoSmithKline Pharmaceuticals Oral presentation at European Laboratory Robotics Information Group meeting in Cambridge, England April 27, 2006 on using Covaris process for cell lysis (E.coli) GSK ELRIG 2006 Presentation  (1.52mb)   Charles River Laboratories Poster presented at AAPS 2006 for use of Covaris AFA to homogenize Peripheral Blood Mononuclear Cells (PBMCs) Charles River Labs 2006 Poster  (183kb)   Amgen 2006 Poster presented at the 2006 ASMS for a method for the determination of free drug in mouse brain by acoustic homogenization, ultracentrifugation and LC-MS/MS ASMS Amgen 2006 Poster (1.64mb)   Amgen 2007 Poster presented at the 2007 ASMS for a method of tissue analysis using homogenization with Covaris AFA technology ASMS Amgen 2007 Poster (411kb)   Application Area Compound Dissolution / HTS GlaxoSmithKline Pharmaceuticals Poster presented at SBS 2005 on implementation of Covaris AFA throughout the Drug Discovery pipeline GSK 2005 Poster (680kb)   GlaxoSmithKline Pharmaceuticals Poster presented at LabAutomation 2006 for use of Covaris AFA in Compound Management applications GSK LabAuto 2006 Poster (811kb)   GlaxoSmithKline Pharmaceuticals Oral presentation at Miptec meeting in Basel, Switzerland 2006 using the Covaris technology for applications in compound management, chemistry and high-throughput screening GSK Miptec 2006 Presentation (453kb)   GlaxoSmithKline Pharmaceuticals Presentation given at the 2006 Society for Biomolecular Sciences (SBS) Sample Management Special Interest Group comparing Covaris AFA technology vs. conventional sonication for compound management applications Covaris SBS 2006 Presentation (890kb)   Application Area Specialized Applications Broad Institute Poster presented at AGBT 2006 for use of Covaris AFA to improve DNA shearing methodology Broad AGBT 2006 Poster  (105kb)   GlaxoSmithKline Pharmaceuticals Poster presented at 2007 DMDG for use of Covaris AFA technology in Psychiatry CEED DMPK GSK DMDG 2007 Poster (680kb)   Florida Gulf Coast University Presentation for the American Academy of Sciences, February 2007, which describes the method of extraction of DNA from bone using Covaris AFA technology Forensics Samples Proceedings (19kb)   Covaris AFA Ultra Sonication Benefits   Covaris AFA Ultra Sonication Benefits 2007 poster illustrating the benefits of Covaris AFA ultra sonication on the HTS process from compound master to HTS assay plate Covaris AFA Ultra Poster (63kb)
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