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Acoustics by Covaris
S-series
High Performance,
Single Tube
Sample Preparation

S-series
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Overview
The Covaris S-series are advanced instruments based on technologies developed from both medical diagnostic imaging and therapeutic ultrasound industries. Covaris has developed numerous applications for the biological laboratory; using our S-series products, many processes can be completed within seconds.

Key features Benefits
Isothermal processing No heat damage, higher recovery
Non-contact, in closed vessel No cross contamination, no clean-up, no aerosol
Precisely controlled energy delivery Standardized processes, highly reproducible

What They Do
The scalable energy of the S-series systems processes various volumes and masses in seconds. Sample integrity is maintained as the Covaris process is non-contact (for example, no evaporation or probe contact) and non-ionizing. As the process occurs in a closed vessel, there is no cross-talk between samples. Additionally, closed tube processing allows head-space modification, such as a biochemically inert gas for labile molecules. Isothermal, reflux processes from 4ºC to 40ºC are standard.

Broad Range of Applications:

  • Tissue disruption and homogenization
  • Sample extraction for metabolic and proteomic profiling
  • DNA shearing
  • Chromatin shearing
  • RNA extraction
  • Cell lysis
  • Compound dissolution
  • Compound formulation
  • ADME/Tox
Instrument Models:
Covaris S2 is used in most applications. We may recommend other S-series models for certain specialized projects. S-series instruments may also be integrated into robotic systems for enhanced automation. Please contact Covaris for further details. The standard S-series configuration uses a borosilicate culture tube with polypropylene screw-top closure. Additionally, the process enables tubes to have surface modifications for special applications (e.g., parylene or silane coating).

Our proprietary software, SonoLab™, runs on Windows® XP with easy-to-use-tools. The system may also be configured for ActiveX control.

The bench-top size system is approximately 21 cm wide, 31 cm high and 52 cm deep. The unit includes a notebook computer and, if required, a chiller may be readily attached.






Additional Resources
PDF
S-series Datasheet

PDF
Consumables Datasheet

PDF
Supply Catalog


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