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Current Protocols
Chromatin Shearing
truChIP High Cell Chromatin Shearing Kit with Non-ionic Shearing Buffer
truChIP High Cell Chromatin Shearing Kit with SDS Shearing Buffer
truChIP Low Cell Chromatin Shearing Kit with Non-ionic Shearing Buffer
truChIP Low Cell Chromatin Shearing Kit with SDS Shearing Buffer
truChIP Tissue Chromatin Shearing Kit with SDS Shearing Buffer
If you are using buffers other than the ones used in the above two protocols, please
contact Covaris
Chromatin Shearing Protocols are subject to change. Please download updated protocols from this site.
DNA Shearing for the S2 / E210
DNA shearing protocol for fragments <1.5kb
DNA shearing protocol for fragments 2.0kb (CLEAR tube)
DNA shearing protocol for fragments 3.0kb (BLUE tube)
DNA shearing protocol for fragments 5.0kb (RED tube)
Agilent SureSelect protocol (including Covaris DNA shearing steps)
Quick Reference Guide for S2-E210
DNA Shearing for the 220 Series
DNA shearing protocol for fragments <1.5kb
DNA shearing protocol for fragments 2.0kb (CLEAR tube)
DNA shearing protocol for fragments 3.0kb (BLUE tube)
DNA shearing protocol for fragments 5.0kb (RED tube)
Quick Reference Guide for S220 and E220 Protocols
Quick Reference Guide for LE220 Protocols
Low Volume DNA Shearing
Low Volume DNA Shearing Protocol
RNA Fragmentation
mRNA and total RNA fragmentation
Dry Pulverization
Dry Tissue Pulverization with the CryoPrep
Additional Resources
Quick Reference Guide for S220 and E220 Protocols
PN/010111 Product Insert for the E210 Intensifier
PN/010112 Product Insert for 96microTUBE Plate
Quick Reference Guide for LE220 Protocols
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