Disruption of tablets for QC monitoring of Active Pharmaceutical Ingredients (API) is a time consuming, laborious, and uncontrolled process. This is particularly onerous when the formulation is slow release. The ability of AFA™ to focus large amounts of power into a small sample size is therefore ideally suited to this closed vessel application. The Covaris systems may also be run at elevated temperatures (e.g., 37ºC).

A number of features and benefits are listed below:

Feature	Benefit
Non-contact	No contamination and compliance issues
Controllable Mechanical Energy	Accelerates the breakdown of all tablet formulations
Isothermal	No degradation issues Maintain temperature at set-point between 4 to 40ºC
Closed tube	Safe - no aerosol risk No sample cross-talk No clean-up, nor decontamination
Automated on E-200	High throughput batch work possible